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Espruino is a JavaScript interpreter for low-power Microcontrollers. This site is both a support community for Espruino and a place to share what you are working on.
@Gordon
I notice in this one it's connecting to COM3 and getting no answer, when previously it was COM4. Do you have different boards that you're using? It could be possible that you're just connecting to a COM port belonging to a different bit of hardware (it's happened before!).
Also, is there any chance that another application is trying to use the COM port at the same time? I think you're using the Chrome Web App rather than the Native IDE? But if you use the Native IDE does it work any better? It's worth a try I guess!