Call of object.method from event gets empty object

I do not have much experience with JavaScript (have quite a bit with Java).
It is weird issue from my perspective. If I assign an object's method call to event, it runs in empty object instance. All fields are empty. But if I wrap object's method into a function, and put into event, it runs ok. Is it normal?
Example:

const O = {
  A:"", B:0,
  M : function(){
    this.A = this.A + "*";
    this.B = this.B + 1;
    print(this.A," - ", this.B);
  }
};

function F(){
  O.M();
}

// uncomment one  or another call and run
//setInterval(O.M, 1000); // method M runs in empty object instance
//setInterval(F, 1000); // method M runs in populated object instance

Output of direct method assignment

undefined*  -  NaN
undefined**  -  NaN
undefined***  -  NaN

Output of wrapped method assignment

*  -  1
**  -  2
***  -  3