WS2812B (neopixel) and Graphics lib: custom matrix configuration

I got a several 4x4 neopixel-compatible modules:

and would like to string several of them horizontally to create a 16x4 matrix. Can the Graphics library work with this configuration?

I know in the RGB123 example you can create an array buffer x*y but wondering if it will work with arbitrary rows and columns since in regard to the wirings of arbitrary modules.

Thanks!

*edit: I need to do 12X4 instead of 16X4