115200 would be a huge help - the maximum frame rate Glediator could send over that would be 51fps (20ms), but it only takes 6.75ms to send it to the LEDs - so I think you stand a good chance with that.
Espruino is a JavaScript interpreter for low-power Microcontrollers. This site is both a support community for Espruino and a place to share what you are working on.
115200 would be a huge help - the maximum frame rate Glediator could send over that would be 51fps (20ms), but it only takes 6.75ms to send it to the LEDs - so I think you stand a good chance with that.