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Espruino is a JavaScript interpreter for low-power Microcontrollers. This site is both a support community for Espruino and a place to share what you are working on.
@Robin
Sat 2019.06.15
The web page content provides sufficient information in order for size comparison.
The Pico, sans USB connector tab, has a slightly smaller footprint than the MDBT42Q breakout, although the MDBT42Q is a pin row width, 0.1" wider and two pins longer.
In the Tutorial Section: Quick Start Best Practices - increasing battery life
An existing forum post: Powering with a coin cell
As both possess onboard regulators, what about a drone battery, ~0.75"x~0.5"? Getting around the charge plug and extra wire might be problematic, and the fact a separate rechargeable board or recharger would be needed.