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Espruino is a JavaScript interpreter for low-power Microcontrollers. This site is both a support community for Espruino and a place to share what you are working on.
George
Good luck... I was looking up whether it is possible to change the pin config to inverted logic as many devices allow... but did not find a thing (assuming you work w/ STM32F series of processors...). I hoped to find a possibility where you would poke some bit into some register and it magically happens... Since Neopixel is burned into the firmware, you may need a separate build...
You did not answer whether you need a level shifter...
Least messing is option 2.