"Serial1.on('data', function (data) {......" not works for me, is works for any other ??

Sorry, just now, I updated the espruino code to the latest one.
It is working perfectly. This is my test code :

var status=0;
function swap() {
    status = !status;
    digitalWrite(D2, status);
}

var Serial3 = new Serial();
Serial3.setup(9600, {rx:D4,tx:D5});
//Serial1.setup(9600);
Serial3.on('data', function (data) { 
  console.log(data);
  swap(); 
});

var buf1 = new ArrayBuffer();
buf1 = [0x01, 0x03, 0x00, 0x00, 0x00, 0x05, 0x85, 0xC9];
var count = 0;
setInterval(function() {
  if (count > 7) {
    count = 0;
  }
  console.log("send data", count);
  Serial3.write(buf1);
  count += 1;
}, 2000);

However, if we increase the baud-rate to 115200, the ESP will be crashed.
But, for my application, it is Ok. For displaying the data to the LED matrix display, that required highspeed UART at 115200, I will use hardware serial.

Thanks for your help, @MaBe