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Espruino is a JavaScript interpreter for low-power Microcontrollers. This site is both a support community for Espruino and a place to share what you are working on.
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It is possible but EL wire work with 100V at a few hundreds hertz. So need to add some interface circuit to drive EL wire with the Espruino.
The how many answer depends on the possibilities of the interface circuit. I have seen an EL shield at seeedstudio for Arduino which was able to drive four EL wires. Each of them could be powered on/off.
They also have another one that maybe more interesting working both on 3V and 5V but driving only one EL wire