I see no reason why a normal load cell wouldn't work.
I don't think anyone has done that yet with the Espruino (if they did, they haven't talked about it), but just about anything that can be read with an Arduino can be read with the Espruino.
Espruino is a JavaScript interpreter for low-power Microcontrollers. This site is both a support community for Espruino and a place to share what you are working on.
I see no reason why a normal load cell wouldn't work.
I don't think anyone has done that yet with the Espruino (if they did, they haven't talked about it), but just about anything that can be read with an Arduino can be read with the Espruino.