Hi! Yes, a 12v charger is nice and easy and safe, and would work with most boards.
The Pico itself will run direct from the car's 12v though (it'll do up to 16v, so fine while the engine is running too). Just connect it between the VBAT and GND pins (opposite sides of the board to each other).
Some people have reported that trying to use USB while the board is powered from 12v doesn't work that well, but personally I haven't really noticed any problems. While I don't have one in my car I used one powered from a car battery for ages as a plant waterer :)
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